ENaC and Hypertension Essay Example | Topics and Well Written Essays - 250 words

ENaC and Hypertension - Essay ExampleHowever, for individuals past the age of 45, the incidences of hypertension put on and affect much women than men 1. In the U.S. 25% of Americans suffer from hypertension. High blood squeeze varies amongst heathen groups where African Americans have the highest risk for hypertension among Americans. Forty percent of African Americans have hypertension and it is more likely to be manifested at an earlier age than Caucasians. Hypertension is the primary cause of 25% of deaths in America today. Additionally, 47% of individuals with hypertension have blood pressure that is not under control. Most of hypertensives be resistant to common medications. They have to take more than one medication to render their blood pressure stable3. The pathogenesis of hypertension remains unknown. Blood pressure must be regulated to prevent electronegative of vital organs. From this point, studying the molecular basis and human protein level of this disease is nee ded for early detecting and for distinguishing markers and designing targeting therapy.The kidneys play a major role in hypertension mainly in the nutrition of sodium balance within the body. They also maintain the balance of the gaudiness of extracellular fluid that leads to the eagle-eyed term control of blood pressure. Therefore, any imbalance in sodium entry expands the blood volume leading to hormonal and vascular change in the kidneys and increasing blood pressure 2.In sexual congress to the various mechanisms involved in hypertensions inheritance, two major categories exist. These argon Mendelian hypertension and essential hypertension. The Mendelian form of hypertension occurs because of a single or small number of genes which are defective. These can also be either dominant or recessive 4. In contrast, essential hypertension, which is a heterogeneous disorder of hypertension, is more complex and does not follow the kind of inheritance